| Des Moines to Shoreham-by-Sea | 4,204.91 mi (6,767.15 km) |
| Des Moines to Shotley Bridge | 4,009.15 mi (6,452.10 km) |
| Des Moines to Shrewsbury | 4,048.31 mi (6,515.12 km) |
| Des Moines to Sidcup | 4,197.63 mi (6,755.43 km) |
| Des Moines to Sidmouth | 4,098.47 mi (6,595.85 km) |
| Des Moines to Sileby | 4,107.68 mi (6,610.68 km) |
| Des Moines to Sittingbourne | 4,224.21 mi (6,798.21 km) |
| Des Moines to Skegness | 4,145.55 mi (6,671.62 km) |
| Des Moines to Skelmersdale | 4,019.70 mi (6,469.08 km) |
| Des Moines to Skipton | 4,033.42 mi (6,491.16 km) |
| Des Moines to Sleaford | 4,123.60 mi (6,636.29 km) |
| Des Moines to Slough | 4,169.22 mi (6,709.72 km) |
| Des Moines to Small Heath | 4,089.55 mi (6,581.49 km) |
| Des Moines to Smethwick | 4,084.33 mi (6,573.09 km) |
| Des Moines to Snaresbrook | 4,188.66 mi (6,741.00 km) |
