| Des Moines to Sesena | 4,466.10 mi (7,187.49 km) |
| Des Moines to Sestao | 4,373.11 mi (7,037.84 km) |
| Des Moines to Sevilla | 4,475.02 mi (7,201.85 km) |
| Des Moines to Sevilla La Nueva | 4,442.22 mi (7,149.06 km) |
| Des Moines to Silla | 4,638.61 mi (7,465.12 km) |
| Des Moines to Silleda | 4,171.53 mi (6,713.43 km) |
| Des Moines to Sitges | 4,656.91 mi (7,494.57 km) |
| Des Moines to Socuellamos | 4,537.40 mi (7,302.24 km) |
| Des Moines to Soller | 4,755.20 mi (7,652.75 km) |
| Des Moines to Solsona | 4,614.04 mi (7,425.58 km) |
| Des Moines to Son Servera | 4,789.22 mi (7,707.51 km) |
| Des Moines to Sonseca | 4,470.70 mi (7,194.89 km) |
| Des Moines to Sopelana | 4,371.56 mi (7,035.34 km) |
| Des Moines to Soria | 4,454.97 mi (7,169.59 km) |
| Des Moines to Suances | 4,324.45 mi (6,959.54 km) |
