| Depew to Worthington (Ohio) | 296.18 mi (476.66 km) |
| Depew to Wright (Florida) | 966.09 mi (1,554.78 km) |
| Depew to Wyandanch (New York) | 312.84 mi (503.47 km) |
| Depew to Wyandotte (Michigan) | 231.62 mi (372.76 km) |
| Depew to Wylie (Texas) | 1,182.05 mi (1,902.33 km) |
| Depew to Wyndham (Virginia) | 365.18 mi (587.70 km) |
| Depew to Wyoming (Michigan) | 354.31 mi (570.20 km) |
| Depew to Wyomissing (Pennsylvania) | 227.39 mi (365.95 km) |
| Depew to Xenia (Ohio) | 351.55 mi (565.76 km) |
| Depew to Yakima (Washington) | 2,044.55 mi (3,290.39 km) |
| Depew to Yankton (South Dakota) | 943.92 mi (1,519.10 km) |
| Depew to Yauco (Puerto Rico) | 1,853.45 mi (2,982.84 km) |
| Depew to Yazoo City (Mississippi) | 941.25 mi (1,514.80 km) |
| Depew to Yeadon (Pennsylvania) | 272.63 mi (438.75 km) |
| Depew to Yelm (Washington) | 2,138.13 mi (3,440.99 km) |
