| Depew to Wayne (Michigan) | 242.18 mi (389.75 km) |
| Depew to Waynesboro (Pennsylvania) | 225.92 mi (363.58 km) |
| Depew to Waynesboro (Virginia) | 334.88 mi (538.93 km) |
| Depew to Weatherford (Oklahoma) | 1,180.65 mi (1,900.08 km) |
| Depew to Weatherford (Texas) | 1,250.43 mi (2,012.38 km) |
| Depew to Webb City (Missouri) | 922.43 mi (1,484.51 km) |
| Depew to Webster (Texas) | 1,296.07 mi (2,085.83 km) |
| Depew to Webster Groves (Missouri) | 678.27 mi (1,091.57 km) |
| Depew to Weddington (North Carolina) | 555.87 mi (894.59 km) |
| Depew to Weigelstown (Pennsylvania) | 224.27 mi (360.93 km) |
| Depew to Weirton (West Virginia) | 198.03 mi (318.70 km) |
| Depew to Wekiwa Springs (Florida) | 993.66 mi (1,599.14 km) |
| Depew to Welby (Colorado) | 1,372.26 mi (2,208.44 km) |
| Depew to Wellington (Colorado) | 1,357.58 mi (2,184.81 km) |
| Depew to Wellington (Florida) | 1,127.30 mi (1,814.21 km) |
