| Depew to Spout Springs (North Carolina) | 528.12 mi (849.93 km) |
| Depew to Spring (Texas) | 1,278.70 mi (2,057.87 km) |
| Depew to Spring Creek (Nevada) | 1,890.12 mi (3,041.86 km) |
| Depew to Spring Hill (Florida) | 1,019.69 mi (1,641.04 km) |
| Depew to Spring Hill (Tennessee) | 660.92 mi (1,063.64 km) |
| Depew to Spring Lake (North Carolina) | 534.15 mi (859.63 km) |
| Depew to Spring Valley (California) | 2,182.49 mi (3,512.37 km) |
| Depew to Spring Valley (Nevada) | 1,988.40 mi (3,200.03 km) |
| Depew to Spring Valley (New York) | 269.26 mi (433.34 km) |
| Depew to Springboro (Ohio) | 368.85 mi (593.61 km) |
| Depew to Springdale (Arkansas) | 943.09 mi (1,517.75 km) |
| Depew to Springdale (New Jersey) | 285.22 mi (459.02 km) |
| Depew to Springdale (Ohio) | 390.85 mi (629.01 km) |
| Depew to Springfield (Illinois) | 607.48 mi (977.65 km) |
| Depew to Springfield (Massachusetts) | 318.68 mi (512.86 km) |
