| Depew to Somersworth (New Hampshire) | 395.12 mi (635.89 km) |
| Depew to Somerton (Arizona) | 2,072.66 mi (3,335.62 km) |
| Depew to Somerville (Massachusetts) | 387.90 mi (624.26 km) |
| Depew to Somerville (New Jersey) | 265.96 mi (428.01 km) |
| Depew to Sonoma (California) | 2,291.39 mi (3,687.63 km) |
| Depew to Soquel (California) | 2,300.62 mi (3,702.49 km) |
| Depew to South Bend (Indiana) | 395.80 mi (636.99 km) |
| Depew to South Bradenton (Florida) | 1,089.42 mi (1,753.26 km) |
| Depew to South Burlington (Vermont) | 294.12 mi (473.34 km) |
| Depew to South Charleston (West Virginia) | 352.93 mi (567.98 km) |
| Depew to South Daytona (Florida) | 958.32 mi (1,542.26 km) |
| Depew to South El Monte (California) | 2,192.43 mi (3,528.37 km) |
| Depew to South Elgin (Illinois) | 493.72 mi (794.57 km) |
| Depew to South Euclid (Ohio) | 173.25 mi (278.81 km) |
| Depew to South Farmingdale (New York) | 310.19 mi (499.20 km) |
