| Depew to Smyrna (Delaware) | 297.41 mi (478.63 km) |
| Depew to Smyrna (Georgia) | 699.52 mi (1,125.77 km) |
| Depew to Smyrna (Tennessee) | 635.29 mi (1,022.39 km) |
| Depew to Snellville (Georgia) | 688.00 mi (1,107.22 km) |
| Depew to Snoqualmie (Washington) | 2,095.89 mi (3,373.01 km) |
| Depew to Snyder (Texas) | 1,395.72 mi (2,246.20 km) |
| Depew to Socastee (South Carolina) | 637.58 mi (1,026.08 km) |
| Depew to Socorro (Texas) | 1,692.70 mi (2,724.14 km) |
| Depew to Soddy-Daisy (Tennessee) | 632.08 mi (1,017.24 km) |
| Depew to Solana Beach (California) | 2,187.61 mi (3,520.63 km) |
| Depew to Soledad (California) | 2,285.81 mi (3,678.66 km) |
| Depew to Solon (Ohio) | 175.33 mi (282.16 km) |
| Depew to Somers Point (New Jersey) | 327.33 mi (526.78 km) |
| Depew to Somerset (Kentucky) | 509.52 mi (820.00 km) |
| Depew to Somerset (New Jersey) | 273.04 mi (439.41 km) |
