| Depew to Savannah (Georgia) | 764.03 mi (1,229.59 km) |
| Depew to Sayreville (New Jersey) | 282.16 mi (454.10 km) |
| Depew to Sayville (New York) | 325.60 mi (524.01 km) |
| Depew to Scaggsville (Maryland) | 277.21 mi (446.13 km) |
| Depew to Scarsdale (New York) | 285.81 mi (459.97 km) |
| Depew to Schaumburg (Illinois) | 481.62 mi (775.10 km) |
| Depew to Schenectady (New York) | 242.03 mi (389.50 km) |
| Depew to Schererville (Indiana) | 457.84 mi (736.83 km) |
| Depew to Schertz (Texas) | 1,420.97 mi (2,286.84 km) |
| Depew to Schiller Park (Illinois) | 471.73 mi (759.18 km) |
| Depew to Schofield Barracks (Hawaii) | 4,695.28 mi (7,556.32 km) |
| Depew to Scotchtown (New York) | 243.13 mi (391.29 km) |
| Depew to Scottdale (Georgia) | 697.81 mi (1,123.01 km) |
| Depew to Scotts Valley (California) | 2,302.21 mi (3,705.05 km) |
| Depew to Scottsbluff (Nebraska) | 1,270.95 mi (2,045.39 km) |
