| Depew to Darby (Pennsylvania) | 272.96 mi (439.28 km) |
| Depew to Dardenne Prairie (Missouri) | 690.35 mi (1,111.01 km) |
| Depew to Darien (Illinois) | 480.47 mi (773.24 km) |
| Depew to Davenport (Iowa) | 615.44 mi (990.45 km) |
| Depew to Davidson (North Carolina) | 525.57 mi (845.82 km) |
| Depew to Davie (Florida) | 1,166.47 mi (1,877.25 km) |
| Depew to Davis (California) | 2,248.25 mi (3,618.21 km) |
| Depew to Dayton (Nevada) | 2,121.82 mi (3,414.74 km) |
| Depew to Dayton (Ohio) | 357.75 mi (575.74 km) |
| Depew to Daytona Beach (Florida) | 956.70 mi (1,539.66 km) |
| Depew to De Pere (Wisconsin) | 479.80 mi (772.17 km) |
| Depew to De Witt (New York) | 132.82 mi (213.76 km) |
| Depew to Dearborn (Michigan) | 232.94 mi (374.88 km) |
| Depew to Dearborn Heights (Michigan) | 236.09 mi (379.94 km) |
| Depew to DeBary (Florida) | 980.28 mi (1,577.61 km) |
