| Depew to Clarksdale (Mississippi) | 878.07 mi (1,413.12 km) |
| Depew to Clarkston (Georgia) | 696.21 mi (1,120.45 km) |
| Depew to Clarksville (Indiana) | 487.32 mi (784.27 km) |
| Depew to Clarksville (Tennessee) | 633.87 mi (1,020.11 km) |
| Depew to Clawson (Michigan) | 227.13 mi (365.53 km) |
| Depew to Clay (Alabama) | 766.79 mi (1,234.03 km) |
| Depew to Clayton (California) | 2,273.97 mi (3,659.61 km) |
| Depew to Clayton (Missouri) | 675.16 mi (1,086.57 km) |
| Depew to Clayton (North Carolina) | 501.30 mi (806.77 km) |
| Depew to Clayton (Ohio) | 359.33 mi (578.29 km) |
| Depew to Clearfield (Utah) | 1,704.00 mi (2,742.32 km) |
| Depew to Clearlake (California) | 2,282.97 mi (3,674.08 km) |
| Depew to Clearwater (Florida) | 1,056.38 mi (1,700.08 km) |
| Depew to Cleburne (Texas) | 1,252.29 mi (2,015.37 km) |
| Depew to Clemmons (North Carolina) | 483.71 mi (778.46 km) |
