| Denver to Sanford (Maine) | 1,768.51 mi (2,846.14 km) |
| Denver to Sanford (North Carolina) | 1,431.77 mi (2,304.21 km) |
| Denver to Sanger (California) | 823.40 mi (1,325.13 km) |
| Denver to Santa Ana (California) | 830.48 mi (1,336.52 km) |
| Denver to Santa Barbara (California) | 895.76 mi (1,441.59 km) |
| Denver to Santa Clara (California) | 936.64 mi (1,507.38 km) |
| Denver to Santa Clara (Oregon) | 983.01 mi (1,582.00 km) |
| Denver to Santa Clarita (California) | 835.36 mi (1,344.39 km) |
| Denver to Santa Cruz (California) | 947.60 mi (1,525.02 km) |
| Denver to Santa Fe (New Mexico) | 289.66 mi (466.17 km) |
| Denver to Santa Fe (Texas) | 905.90 mi (1,457.91 km) |
| Denver to Santa Fe Springs (California) | 831.70 mi (1,338.49 km) |
| Denver to Santa Maria (California) | 916.29 mi (1,474.63 km) |
| Denver to Santa Monica (California) | 848.63 mi (1,365.74 km) |
| Denver to Santa Paula (California) | 865.66 mi (1,393.15 km) |
