| Denver to Enumclaw (Washington) | 996.97 mi (1,604.46 km) |
| Denver to Ephrata (Pennsylvania) | 1,513.02 mi (2,434.97 km) |
| Denver to Erie (Colorado) | 21.11 mi (33.97 km) |
| Denver to Erie (Pennsylvania) | 1,300.07 mi (2,092.25 km) |
| Denver to Erlanger (Kentucky) | 1,082.40 mi (1,741.96 km) |
| Denver to Escanaba (Michigan) | 989.73 mi (1,592.82 km) |
| Denver to Escondido (California) | 816.82 mi (1,314.54 km) |
| Denver to Española (New Mexico) | 267.64 mi (430.73 km) |
| Denver to Essex (Maryland) | 1,509.01 mi (2,428.51 km) |
| Denver to Essex Junction (Vermont) | 1,649.17 mi (2,654.08 km) |
| Denver to Estelle (Louisiana) | 1,080.03 mi (1,738.14 km) |
| Denver to Estero (Florida) | 1,614.95 mi (2,599.01 km) |
| Denver to Euclid (Ohio) | 1,226.65 mi (1,974.10 km) |
| Denver to Eufaula (Alabama) | 1,227.20 mi (1,974.98 km) |
| Denver to Eugene (Oregon) | 981.38 mi (1,579.37 km) |
