| Denison to Southern Pines (North Carolina) | 982.02 mi (1,580.42 km) |
| Denison to Southfield (Michigan) | 939.44 mi (1,511.89 km) |
| Denison to Southgate (Michigan) | 930.99 mi (1,498.28 km) |
| Denison to Southlake (Texas) | 65.06 mi (104.71 km) |
| Denison to Spanaway (Washington) | 1,629.62 mi (2,622.62 km) |
| Denison to Spanish Fork (Utah) | 938.29 mi (1,510.03 km) |
| Denison to Spanish Lake (Missouri) | 496.10 mi (798.40 km) |
| Denison to Spanish Springs (Nevada) | 1,337.62 mi (2,152.69 km) |
| Denison to Sparks (Nevada) | 1,339.03 mi (2,154.97 km) |
| Denison to Spartanburg (South Carolina) | 839.15 mi (1,350.48 km) |
| Denison to Spearfish (South Dakota) | 835.44 mi (1,344.50 km) |
| Denison to Speedway (Indiana) | 706.55 mi (1,137.09 km) |
| Denison to Spencer (Iowa) | 652.62 mi (1,050.30 km) |
| Denison to Spokane (Washington) | 1,445.77 mi (2,326.75 km) |
| Denison to Spokane Valley (Washington) | 1,437.97 mi (2,314.18 km) |
