| Defiance to Wayne (Michigan) | 85.30 mi (137.27 km) |
| Defiance to Waynesboro (Pennsylvania) | 371.52 mi (597.91 km) |
| Defiance to Waynesboro (Virginia) | 365.60 mi (588.37 km) |
| Defiance to Weatherford (Oklahoma) | 869.40 mi (1,399.16 km) |
| Defiance to Weatherford (Texas) | 943.69 mi (1,518.72 km) |
| Defiance to Webb City (Missouri) | 611.24 mi (983.69 km) |
| Defiance to Webster (Texas) | 1,011.02 mi (1,627.07 km) |
| Defiance to Webster Groves (Missouri) | 367.74 mi (591.83 km) |
| Defiance to Weddington (North Carolina) | 475.10 mi (764.59 km) |
| Defiance to Weigelstown (Pennsylvania) | 404.98 mi (651.75 km) |
| Defiance to Weirton (West Virginia) | 207.53 mi (333.99 km) |
| Defiance to Wekiwa Springs (Florida) | 885.03 mi (1,424.32 km) |
| Defiance to Welby (Colorado) | 1,083.32 mi (1,743.44 km) |
| Defiance to Wellington (Colorado) | 1,074.63 mi (1,729.45 km) |
| Defiance to Wellington (Florida) | 1,037.73 mi (1,670.07 km) |
