| Defiance to The Villages (Florida) | 865.62 mi (1,393.08 km) |
| Defiance to The Woodlands (Texas) | 988.13 mi (1,590.24 km) |
| Defiance to Thibodaux (Louisiana) | 871.87 mi (1,403.14 km) |
| Defiance to Thomasville (Georgia) | 721.79 mi (1,161.60 km) |
| Defiance to Thomasville (North Carolina) | 438.91 mi (706.37 km) |
| Defiance to Thonotosassa (Florida) | 921.93 mi (1,483.70 km) |
| Defiance to Thornton (Colorado) | 1,081.08 mi (1,739.82 km) |
| Defiance to Thousand Oaks (California) | 1,934.42 mi (3,113.15 km) |
| Defiance to Three Lakes (Florida) | 1,104.17 mi (1,777.00 km) |
| Defiance to Tiffin (Ohio) | 62.66 mi (100.84 km) |
| Defiance to Tifton (Georgia) | 680.04 mi (1,094.42 km) |
| Defiance to Tigard (Oregon) | 1,932.54 mi (3,110.13 km) |
| Defiance to Tillmans Corner (Alabama) | 769.72 mi (1,238.75 km) |
| Defiance to Timberlake (Virginia) | 387.04 mi (622.88 km) |
| Defiance to Timberlane (Louisiana) | 849.24 mi (1,366.72 km) |
