| Defiance to Spout Springs (North Carolina) | 505.75 mi (813.93 km) |
| Defiance to Spring (Texas) | 989.88 mi (1,593.07 km) |
| Defiance to Spring Creek (Nevada) | 1,619.90 mi (2,606.98 km) |
| Defiance to Spring Hill (Florida) | 890.53 mi (1,433.18 km) |
| Defiance to Spring Hill (Tennessee) | 406.56 mi (654.30 km) |
| Defiance to Spring Lake (North Carolina) | 511.99 mi (823.97 km) |
| Defiance to Spring Valley (California) | 1,880.96 mi (3,027.12 km) |
| Defiance to Spring Valley (Nevada) | 1,694.98 mi (2,727.81 km) |
| Defiance to Spring Valley (New York) | 536.18 mi (862.89 km) |
| Defiance to Springboro (Ohio) | 119.03 mi (191.55 km) |
| Defiance to Springdale (Arkansas) | 633.59 mi (1,019.66 km) |
| Defiance to Springdale (New Jersey) | 502.12 mi (808.09 km) |
| Defiance to Springdale (Ohio) | 137.65 mi (221.52 km) |
| Defiance to Springfield (Illinois) | 296.63 mi (477.38 km) |
| Defiance to Springfield (Massachusetts) | 612.32 mi (985.44 km) |
