| Defiance to Saddlebrooke (Arizona) | 1,575.53 mi (2,535.57 km) |
| Defiance to Safety Harbor (Florida) | 921.94 mi (1,483.72 km) |
| Defiance to Saginaw (Michigan) | 149.28 mi (240.24 km) |
| Defiance to Saginaw (Texas) | 921.06 mi (1,482.30 km) |
| Defiance to Sahuarita (Arizona) | 1,602.17 mi (2,578.44 km) |
| Defiance to Saks (Alabama) | 529.30 mi (851.82 km) |
| Defiance to Salem (Massachusetts) | 696.88 mi (1,121.52 km) |
| Defiance to Salem (Ohio) | 184.93 mi (297.62 km) |
| Defiance to Salem (Oregon) | 1,947.71 mi (3,134.53 km) |
| Defiance to Salem (Virginia) | 359.51 mi (578.57 km) |
| Defiance to Salem Lakes (Wisconsin) | 212.11 mi (341.35 km) |
| Defiance to Salida (California) | 1,958.55 mi (3,151.98 km) |
| Defiance to Salina (Kansas) | 720.39 mi (1,159.36 km) |
| Defiance to Salinas (California) | 2,010.75 mi (3,235.99 km) |
| Defiance to Salisbury (Maryland) | 506.94 mi (815.85 km) |
