| Defiance to Oakley (California) | 1,983.84 mi (3,192.68 km) |
| Defiance to Oakton (Virginia) | 408.21 mi (656.96 km) |
| Defiance to Oakville (Missouri) | 371.40 mi (597.71 km) |
| Defiance to Oatfield (Oregon) | 1,923.41 mi (3,095.44 km) |
| Defiance to Ocala (Florida) | 845.46 mi (1,360.64 km) |
| Defiance to Ocean Acres (New Jersey) | 539.99 mi (869.04 km) |
| Defiance to Ocean City (New Jersey) | 532.83 mi (857.50 km) |
| Defiance to Ocean Pines (Maryland) | 528.04 mi (849.80 km) |
| Defiance to Ocean Pointe (Hawaii) | 4,429.18 mi (7,128.08 km) |
| Defiance to Ocean Springs (Mississippi) | 790.70 mi (1,272.50 km) |
| Defiance to Oceanside (California) | 1,882.46 mi (3,029.53 km) |
| Defiance to Oceanside (New York) | 561.28 mi (903.29 km) |
| Defiance to Ocoee (Florida) | 892.00 mi (1,435.54 km) |
| Defiance to Oconomowoc (Wisconsin) | 245.85 mi (395.66 km) |
| Defiance to Odenton (Maryland) | 432.79 mi (696.51 km) |
