| Defiance to Monticello (Minnesota) | 549.17 mi (883.81 km) |
| Defiance to Montrose (Colorado) | 1,256.84 mi (2,022.69 km) |
| Defiance to Moody (Alabama) | 543.49 mi (874.66 km) |
| Defiance to Moore (Oklahoma) | 819.89 mi (1,319.48 km) |
| Defiance to Moorestown-Lenola (New Jersey) | 501.07 mi (806.39 km) |
| Defiance to Mooresville (North Carolina) | 437.63 mi (704.29 km) |
| Defiance to Moorhead (Minnesota) | 724.42 mi (1,165.84 km) |
| Defiance to Moorpark (California) | 1,931.74 mi (3,108.83 km) |
| Defiance to Moraga (California) | 2,009.20 mi (3,233.49 km) |
| Defiance to Moreno Valley (California) | 1,855.76 mi (2,986.56 km) |
| Defiance to Morgan City (Louisiana) | 886.56 mi (1,426.78 km) |
| Defiance to Morgan Hill (California) | 2,000.63 mi (3,219.70 km) |
| Defiance to Morganton (North Carolina) | 408.98 mi (658.19 km) |
| Defiance to Morgantown (West Virginia) | 258.53 mi (416.07 km) |
| Defiance to Morris (Illinois) | 210.98 mi (339.53 km) |
