| Defiance to Mitchell (South Dakota) | 715.54 mi (1,151.55 km) |
| Defiance to Mitchellville (Maryland) | 430.49 mi (692.81 km) |
| Defiance to Moberly (Missouri) | 443.85 mi (714.31 km) |
| Defiance to Mobile (Alabama) | 761.81 mi (1,226.01 km) |
| Defiance to Modesto (California) | 1,955.92 mi (3,147.76 km) |
| Defiance to Mokena (Illinois) | 182.83 mi (294.24 km) |
| Defiance to Moline (Illinois) | 317.84 mi (511.51 km) |
| Defiance to Moncks Corner (South Carolina) | 609.09 mi (980.23 km) |
| Defiance to Monfort Heights (Ohio) | 145.59 mi (234.30 km) |
| Defiance to Monmouth (Oregon) | 1,958.20 mi (3,151.42 km) |
| Defiance to Monroe (Georgia) | 518.20 mi (833.96 km) |
| Defiance to Monroe (Louisiana) | 739.64 mi (1,190.34 km) |
| Defiance to Monroe (Michigan) | 66.99 mi (107.82 km) |
| Defiance to Monroe (North Carolina) | 480.23 mi (772.86 km) |
| Defiance to Monroe (Ohio) | 126.80 mi (204.06 km) |
