| Defiance to Mineral Wells (Texas) | 953.92 mi (1,535.18 km) |
| Defiance to Minneapolis (Minnesota) | 515.59 mi (829.76 km) |
| Defiance to Minnehaha (Washington) | 1,923.20 mi (3,095.09 km) |
| Defiance to Minneola (Florida) | 888.21 mi (1,429.44 km) |
| Defiance to Minnetonka (Minnesota) | 523.08 mi (841.81 km) |
| Defiance to Minooka (Illinois) | 203.25 mi (327.10 km) |
| Defiance to Minot (North Dakota) | 955.84 mi (1,538.28 km) |
| Defiance to Mint Hill (North Carolina) | 467.23 mi (751.94 km) |
| Defiance to Miramar (Florida) | 1,082.18 mi (1,741.60 km) |
| Defiance to Mishawaka (Indiana) | 97.09 mi (156.26 km) |
| Defiance to Mission (Texas) | 1,311.04 mi (2,109.91 km) |
| Defiance to Mission Bend (Texas) | 1,020.34 mi (1,642.08 km) |
| Defiance to Mission Viejo (California) | 1,888.53 mi (3,039.30 km) |
| Defiance to Missoula (Montana) | 1,511.94 mi (2,433.23 km) |
| Defiance to Missouri City (Texas) | 1,023.35 mi (1,646.92 km) |
