| Defiance to Merrick (New York) | 565.40 mi (909.92 km) |
| Defiance to Merrifield (Virginia) | 411.54 mi (662.31 km) |
| Defiance to Merrillville (Indiana) | 153.71 mi (247.37 km) |
| Defiance to Merritt Island (Florida) | 919.91 mi (1,480.45 km) |
| Defiance to Mesa (Arizona) | 1,590.02 mi (2,558.89 km) |
| Defiance to Mesquite (Nevada) | 1,618.81 mi (2,605.22 km) |
| Defiance to Mesquite (Texas) | 893.44 mi (1,437.85 km) |
| Defiance to Metairie (Louisiana) | 844.64 mi (1,359.32 km) |
| Defiance to Methuen Town (Massachusetts) | 683.18 mi (1,099.47 km) |
| Defiance to Metuchen (New Jersey) | 524.50 mi (844.09 km) |
| Defiance to Mexico (Missouri) | 421.98 mi (679.11 km) |
| Defiance to Miami (Florida) | 1,096.81 mi (1,765.14 km) |
| Defiance to Miami (Oklahoma) | 639.35 mi (1,028.94 km) |
| Defiance to Miami Beach (Florida) | 1,095.45 mi (1,762.95 km) |
| Defiance to Miami Gardens (Florida) | 1,085.62 mi (1,747.14 km) |
