| Defiance to Medford (New York) | 593.36 mi (954.92 km) |
| Defiance to Medford (Oregon) | 1,966.46 mi (3,164.71 km) |
| Defiance to Medina (Ohio) | 130.14 mi (209.44 km) |
| Defiance to Medulla (Florida) | 930.40 mi (1,497.33 km) |
| Defiance to Mehlville (Missouri) | 369.12 mi (594.04 km) |
| Defiance to Melbourne (Florida) | 933.88 mi (1,502.94 km) |
| Defiance to Melissa (Texas) | 866.88 mi (1,395.11 km) |
| Defiance to Melrose (Massachusetts) | 688.73 mi (1,108.40 km) |
| Defiance to Melrose Park (Illinois) | 185.77 mi (298.97 km) |
| Defiance to Melville (New York) | 571.73 mi (920.12 km) |
| Defiance to Melvindale (Michigan) | 92.23 mi (148.43 km) |
| Defiance to Memphis (Florida) | 954.69 mi (1,536.42 km) |
| Defiance to Memphis (Tennessee) | 523.54 mi (842.56 km) |
| Defiance to Menasha (Wisconsin) | 288.86 mi (464.88 km) |
| Defiance to Mendota (California) | 1,944.09 mi (3,128.71 km) |
