| Defiance to Mauldin (South Carolina) | 462.83 mi (744.85 km) |
| Defiance to Maumee (Ohio) | 41.47 mi (66.74 km) |
| Defiance to Maumelle (Arkansas) | 622.60 mi (1,001.98 km) |
| Defiance to Mayagüez (Puerto Rico) | 1,892.17 mi (3,045.16 km) |
| Defiance to Mayfield Heights (Ohio) | 151.81 mi (244.32 km) |
| Defiance to Mays Chapel (Maryland) | 425.55 mi (684.86 km) |
| Defiance to Maywood (California) | 1,904.73 mi (3,065.37 km) |
| Defiance to Maywood (Illinois) | 184.46 mi (296.86 km) |
| Defiance to McAlester (Oklahoma) | 758.89 mi (1,221.31 km) |
| Defiance to McAllen (Texas) | 1,307.09 mi (2,103.56 km) |
| Defiance to McCalla (Alabama) | 570.33 mi (917.86 km) |
| Defiance to McComb (Mississippi) | 771.90 mi (1,242.26 km) |
| Defiance to McDonough (Georgia) | 541.93 mi (872.15 km) |
| Defiance to McFarland (California) | 1,912.25 mi (3,077.47 km) |
| Defiance to McHenry (Illinois) | 215.03 mi (346.05 km) |
