| Defiance to Lowell (Indiana) | 158.54 mi (255.15 km) |
| Defiance to Lowell (Massachusetts) | 676.02 mi (1,087.95 km) |
| Defiance to Lower Burrell (Pennsylvania) | 247.54 mi (398.38 km) |
| Defiance to Lowes Island (Virginia) | 401.04 mi (645.41 km) |
| Defiance to Lubbock (Texas) | 1,096.40 mi (1,764.48 km) |
| Defiance to Lufkin (Texas) | 896.63 mi (1,442.98 km) |
| Defiance to Luling (Louisiana) | 854.67 mi (1,375.45 km) |
| Defiance to Lumberton (North Carolina) | 543.77 mi (875.11 km) |
| Defiance to Lumberton (Texas) | 939.15 mi (1,511.42 km) |
| Defiance to Lutz (Florida) | 914.45 mi (1,471.67 km) |
| Defiance to Lynbrook (New York) | 559.07 mi (899.74 km) |
| Defiance to Lynchburg (Virginia) | 385.04 mi (619.67 km) |
| Defiance to Lynden (Washington) | 1,909.00 mi (3,072.24 km) |
| Defiance to Lyndhurst (Ohio) | 149.81 mi (241.10 km) |
| Defiance to Lyndon (Kentucky) | 218.32 mi (351.36 km) |
