| Defiance to Lewiston (Maine) | 745.69 mi (1,200.08 km) |
| Defiance to Lewisville (North Carolina) | 416.26 mi (669.90 km) |
| Defiance to Lewisville (Texas) | 896.31 mi (1,442.47 km) |
| Defiance to Lexington (Kentucky) | 223.85 mi (360.25 km) |
| Defiance to Lexington (Nebraska) | 801.36 mi (1,289.67 km) |
| Defiance to Lexington (North Carolina) | 438.47 mi (705.64 km) |
| Defiance to Lexington (South Carolina) | 532.33 mi (856.70 km) |
| Defiance to Lexington Park (Maryland) | 469.69 mi (755.90 km) |
| Defiance to Liberal (Kansas) | 932.58 mi (1,500.85 km) |
| Defiance to Liberty (Missouri) | 548.17 mi (882.20 km) |
| Defiance to Liberty Lake (Washington) | 1,659.59 mi (2,670.85 km) |
| Defiance to Liberty Triangle (Florida) | 851.89 mi (1,370.99 km) |
| Defiance to Libertyville (Illinois) | 198.10 mi (318.82 km) |
| Defiance to Lighthouse Point (Florida) | 1,064.91 mi (1,713.80 km) |
| Defiance to Lilburn (Georgia) | 510.86 mi (822.16 km) |
