| Defiance to La Crosse (Wisconsin) | 390.75 mi (628.84 km) |
| Defiance to La Grande (Oregon) | 1,705.58 mi (2,744.87 km) |
| Defiance to La Grange (Illinois) | 185.02 mi (297.76 km) |
| Defiance to La Grange Park (Illinois) | 185.22 mi (298.08 km) |
| Defiance to La Habra (California) | 1,894.30 mi (3,048.57 km) |
| Defiance to La Homa (Texas) | 1,307.80 mi (2,104.71 km) |
| Defiance to La Marque (Texas) | 1,016.31 mi (1,635.60 km) |
| Defiance to La Mesa (California) | 1,881.98 mi (3,028.75 km) |
| Defiance to La Mirada (California) | 1,898.05 mi (3,054.62 km) |
| Defiance to La Palma (California) | 1,901.23 mi (3,059.73 km) |
| Defiance to La Porte (Indiana) | 123.69 mi (199.07 km) |
| Defiance to La Porte (Texas) | 1,000.79 mi (1,610.61 km) |
| Defiance to La Presa (California) | 1,882.97 mi (3,030.35 km) |
| Defiance to La Puente (California) | 1,891.31 mi (3,043.76 km) |
| Defiance to La Quinta (California) | 1,816.10 mi (2,922.73 km) |
