| Defiance to Iselin (New Jersey) | 526.58 mi (847.44 km) |
| Defiance to Isla Vista (California) | 1,979.16 mi (3,185.15 km) |
| Defiance to Issaquah (Washington) | 1,889.61 mi (3,041.03 km) |
| Defiance to Ithaca (New York) | 412.32 mi (663.56 km) |
| Defiance to Ives Estates (Florida) | 1,085.02 mi (1,746.17 km) |
| Defiance to Jackson (Michigan) | 66.48 mi (106.99 km) |
| Defiance to Jackson (Mississippi) | 698.40 mi (1,123.97 km) |
| Defiance to Jackson (Missouri) | 390.38 mi (628.26 km) |
| Defiance to Jackson (Tennessee) | 457.71 mi (736.62 km) |
| Defiance to Jackson (Wyoming) | 1,350.69 mi (2,173.72 km) |
| Defiance to Jacksonville (Alabama) | 521.85 mi (839.84 km) |
| Defiance to Jacksonville (Arkansas) | 610.96 mi (983.25 km) |
| Defiance to Jacksonville (Florida) | 771.27 mi (1,241.24 km) |
| Defiance to Jacksonville (Illinois) | 326.21 mi (524.99 km) |
| Defiance to Jacksonville (North Carolina) | 590.35 mi (950.07 km) |
