| Defiance to Friendswood (Texas) | 1,014.86 mi (1,633.25 km) |
| Defiance to Frisco (Texas) | 884.33 mi (1,423.19 km) |
| Defiance to Front Royal (Virginia) | 364.87 mi (587.19 km) |
| Defiance to Fruit Cove (Florida) | 787.86 mi (1,267.94 km) |
| Defiance to Fruita (Colorado) | 1,289.55 mi (2,075.34 km) |
| Defiance to Fruitville (Florida) | 969.78 mi (1,560.72 km) |
| Defiance to Fuller Heights (Florida) | 932.65 mi (1,500.96 km) |
| Defiance to Fullerton (California) | 1,894.39 mi (3,048.72 km) |
| Defiance to Fullerton (Pennsylvania) | 465.45 mi (749.06 km) |
| Defiance to Fulshear (Texas) | 1,027.93 mi (1,654.29 km) |
| Defiance to Fulton (Missouri) | 434.50 mi (699.26 km) |
| Defiance to Fulton (New York) | 429.68 mi (691.50 km) |
| Defiance to Fuquay-Varina (North Carolina) | 495.53 mi (797.48 km) |
| Defiance to Gadsden (Alabama) | 510.51 mi (821.58 km) |
| Defiance to Gaffney (South Carolina) | 453.36 mi (729.61 km) |
