| Defiance to Frederick (Maryland) | 387.49 mi (623.61 km) |
| Defiance to Fredericksburg (Texas) | 1,111.02 mi (1,788.02 km) |
| Defiance to Fredericksburg (Virginia) | 419.11 mi (674.50 km) |
| Defiance to Frederickson (Washington) | 1,905.02 mi (3,065.83 km) |
| Defiance to Freeport (Illinois) | 280.19 mi (450.92 km) |
| Defiance to Freeport (New York) | 563.77 mi (907.29 km) |
| Defiance to Freeport (Texas) | 1,052.85 mi (1,694.40 km) |
| Defiance to Fremont (California) | 2,009.21 mi (3,233.51 km) |
| Defiance to Fremont (Nebraska) | 628.20 mi (1,010.99 km) |
| Defiance to Fremont (Ohio) | 65.11 mi (104.78 km) |
| Defiance to French Valley (California) | 1,860.50 mi (2,994.19 km) |
| Defiance to Fresno (California) | 1,913.15 mi (3,078.92 km) |
| Defiance to Fresno (Texas) | 1,022.61 mi (1,645.74 km) |
| Defiance to Fridley (Minnesota) | 518.99 mi (835.24 km) |
| Defiance to Friendly (Maryland) | 428.43 mi (689.50 km) |
