| Defiance to East Rancho Dominguez (California) | 1,907.92 mi (3,070.50 km) |
| Defiance to East Renton Highlands (Washington) | 1,891.47 mi (3,044.03 km) |
| Defiance to East Ridge (Tennessee) | 436.70 mi (702.80 km) |
| Defiance to East Riverdale (Maryland) | 425.09 mi (684.12 km) |
| Defiance to East San Gabriel (California) | 1,895.37 mi (3,050.30 km) |
| Defiance to East St. Louis (Illinois) | 356.48 mi (573.70 km) |
| Defiance to East Wenatchee (Washington) | 1,807.24 mi (2,908.48 km) |
| Defiance to Eastern Goleta Valley (California) | 1,974.43 mi (3,177.54 km) |
| Defiance to Eastlake (Ohio) | 154.08 mi (247.97 km) |
| Defiance to Eastmont (Washington) | 1,895.65 mi (3,050.75 km) |
| Defiance to Easton (Maryland) | 471.54 mi (758.87 km) |
| Defiance to Easton (Pennsylvania) | 478.53 mi (770.11 km) |
| Defiance to Eastpointe (Michigan) | 109.68 mi (176.52 km) |
| Defiance to Eastvale (California) | 1,874.09 mi (3,016.06 km) |
| Defiance to Eatontown (New Jersey) | 543.34 mi (874.43 km) |
