| Defiance to Eagle (Idaho) | 1,629.60 mi (2,622.59 km) |
| Defiance to Eagle Mountain (Utah) | 1,441.45 mi (2,319.79 km) |
| Defiance to Eagle Pass (Texas) | 1,255.53 mi (2,020.58 km) |
| Defiance to Easley (South Carolina) | 456.90 mi (735.31 km) |
| Defiance to East Bakersfield (California) | 1,906.21 mi (3,067.75 km) |
| Defiance to East Bethel (Minnesota) | 525.50 mi (845.71 km) |
| Defiance to East Chicago (Indiana) | 161.90 mi (260.55 km) |
| Defiance to East Cleveland (Ohio) | 145.42 mi (234.03 km) |
| Defiance to East Glenville (New York) | 546.12 mi (878.90 km) |
| Defiance to East Grand Rapids (Michigan) | 131.51 mi (211.64 km) |
| Defiance to East Hemet (California) | 1,847.98 mi (2,974.04 km) |
| Defiance to East Highland Park (Virginia) | 451.69 mi (726.92 km) |
| Defiance to East Honolulu (Hawaii) | 4,414.00 mi (7,103.65 km) |
| Defiance to East Islip (New York) | 583.75 mi (939.45 km) |
| Defiance to East Lake (Florida) | 914.25 mi (1,471.34 km) |
