| Defiance to Darby (Pennsylvania) | 486.54 mi (783.02 km) |
| Defiance to Dardenne Prairie (Missouri) | 379.21 mi (610.28 km) |
| Defiance to Darien (Illinois) | 189.81 mi (305.48 km) |
| Defiance to Davenport (Iowa) | 323.78 mi (521.07 km) |
| Defiance to Davidson (North Carolina) | 443.99 mi (714.54 km) |
| Defiance to Davie (Florida) | 1,075.89 mi (1,731.48 km) |
| Defiance to Davis (California) | 1,974.00 mi (3,176.85 km) |
| Defiance to Dayton (Nevada) | 1,848.21 mi (2,974.41 km) |
| Defiance to Dayton (Ohio) | 104.06 mi (167.47 km) |
| Defiance to Daytona Beach (Florida) | 854.71 mi (1,375.52 km) |
| Defiance to De Pere (Wisconsin) | 287.54 mi (462.75 km) |
| Defiance to De Witt (New York) | 440.95 mi (709.65 km) |
| Defiance to Dearborn (Michigan) | 92.75 mi (149.27 km) |
| Defiance to Dearborn Heights (Michigan) | 90.88 mi (146.26 km) |
| Defiance to DeBary (Florida) | 873.67 mi (1,406.03 km) |
