| Defiance to Crawfordsville (Indiana) | 157.89 mi (254.10 km) |
| Defiance to Crest Hill (Illinois) | 195.13 mi (314.02 km) |
| Defiance to Crestview (Florida) | 738.16 mi (1,187.95 km) |
| Defiance to Crestwood (Illinois) | 176.49 mi (284.03 km) |
| Defiance to Crestwood (Missouri) | 369.93 mi (595.35 km) |
| Defiance to Creve Coeur (Missouri) | 369.06 mi (593.95 km) |
| Defiance to Crofton (Maryland) | 434.89 mi (699.88 km) |
| Defiance to Crossville (Tennessee) | 369.91 mi (595.32 km) |
| Defiance to Crowley (Louisiana) | 885.64 mi (1,425.30 km) |
| Defiance to Crowley (Texas) | 934.39 mi (1,503.76 km) |
| Defiance to Crown Point (Indiana) | 154.84 mi (249.18 km) |
| Defiance to Crystal (Minnesota) | 521.91 mi (839.93 km) |
| Defiance to Crystal Lake (Illinois) | 214.88 mi (345.81 km) |
| Defiance to Cudahy (California) | 1,905.24 mi (3,066.19 km) |
| Defiance to Cudahy (Wisconsin) | 213.02 mi (342.83 km) |
