| Defiance to Channelview (Texas) | 995.99 mi (1,602.89 km) |
| Defiance to Chantilly (Virginia) | 401.35 mi (645.90 km) |
| Defiance to Chaparral (New Mexico) | 1,372.70 mi (2,209.15 km) |
| Defiance to Chapel Hill (North Carolina) | 468.37 mi (753.78 km) |
| Defiance to Charleston (Illinois) | 235.93 mi (379.69 km) |
| Defiance to Charleston (South Carolina) | 632.87 mi (1,018.51 km) |
| Defiance to Charleston (West Virginia) | 249.19 mi (401.03 km) |
| Defiance to Charlotte (North Carolina) | 461.27 mi (742.34 km) |
| Defiance to Charlottesville (Virginia) | 384.64 mi (619.02 km) |
| Defiance to Chaska (Minnesota) | 526.32 mi (847.02 km) |
| Defiance to Chatham (Illinois) | 301.18 mi (484.70 km) |
| Defiance to Chattanooga (Tennessee) | 432.09 mi (695.39 km) |
| Defiance to Cheat Lake (West Virginia) | 261.89 mi (421.48 km) |
| Defiance to Chelsea (Alabama) | 563.49 mi (906.86 km) |
| Defiance to Chelsea (Massachusetts) | 689.93 mi (1,110.33 km) |
