| Defiance to Alderwood Manor (Washington) | 1,899.64 mi (3,057.17 km) |
| Defiance to Aldine (Texas) | 998.13 mi (1,606.33 km) |
| Defiance to Alexander City (Alabama) | 583.92 mi (939.73 km) |
| Defiance to Alexandria (Louisiana) | 823.77 mi (1,325.73 km) |
| Defiance to Alexandria (Minnesota) | 635.25 mi (1,022.34 km) |
| Defiance to Alexandria (Virginia) | 420.76 mi (677.15 km) |
| Defiance to Algonquin (Illinois) | 212.60 mi (342.15 km) |
| Defiance to Alhambra (California) | 1,899.22 mi (3,056.49 km) |
| Defiance to Alice (Texas) | 1,214.01 mi (1,953.76 km) |
| Defiance to Aliso Viejo (California) | 1,893.27 mi (3,046.93 km) |
| Defiance to Allen (Texas) | 880.31 mi (1,416.73 km) |
| Defiance to Allen Park (Michigan) | 90.06 mi (144.93 km) |
| Defiance to Allendale (Michigan) | 142.95 mi (230.06 km) |
| Defiance to Allentown (Pennsylvania) | 466.21 mi (750.29 km) |
| Defiance to Alliance (Ohio) | 170.98 mi (275.16 km) |
