| Defiance to Shoreham-by-Sea | 3,863.61 mi (6,217.88 km) |
| Defiance to Shotley Bridge | 3,690.78 mi (5,939.74 km) |
| Defiance to Shrewsbury | 3,713.84 mi (5,976.84 km) |
| Defiance to Sidcup | 3,860.73 mi (6,213.24 km) |
| Defiance to Sidmouth | 3,750.26 mi (6,035.46 km) |
| Defiance to Sileby | 3,776.55 mi (6,077.77 km) |
| Defiance to Sittingbourne | 3,888.10 mi (6,257.29 km) |
| Defiance to Skegness | 3,819.95 mi (6,147.62 km) |
| Defiance to Skelmersdale | 3,690.73 mi (5,939.65 km) |
| Defiance to Skipton | 3,708.61 mi (5,968.44 km) |
| Defiance to Sleaford | 3,795.54 mi (6,108.33 km) |
| Defiance to Slough | 3,831.41 mi (6,166.06 km) |
| Defiance to Small Heath | 3,755.23 mi (6,043.45 km) |
| Defiance to Smethwick | 3,749.98 mi (6,035.01 km) |
| Defiance to Snaresbrook | 3,852.57 mi (6,200.11 km) |
