| Defiance to Sangeorgiu de Mures | 4,961.71 mi (7,985.10 km) |
| Defiance to Sangeorz-Bai | 4,931.71 mi (7,936.83 km) |
| Defiance to Sannicolau Mare | 4,843.63 mi (7,795.06 km) |
| Defiance to Santana | 4,863.66 mi (7,827.30 km) |
| Defiance to Satu Mare | 4,849.64 mi (7,804.74 km) |
| Defiance to Scobinti | 5,009.32 mi (8,061.71 km) |
| Defiance to Scornicesti | 5,055.87 mi (8,136.64 km) |
| Defiance to Sebes | 4,956.47 mi (7,976.67 km) |
| Defiance to Seini | 4,865.51 mi (7,830.28 km) |
| Defiance to Sfantu-Gheorghe | 5,040.38 mi (8,111.70 km) |
| Defiance to Sibiu | 4,985.12 mi (8,022.78 km) |
| Defiance to Sighetu Marmatiei | 4,878.72 mi (7,851.54 km) |
| Defiance to Sighisoara | 4,988.56 mi (8,028.31 km) |
| Defiance to Simeria | 4,941.15 mi (7,952.01 km) |
| Defiance to Sinaia | 5,055.90 mi (8,136.69 km) |
