| Defiance to Sacile | 4,537.84 mi (7,302.94 km) |
| Defiance to Sala Consilina | 4,893.08 mi (7,874.65 km) |
| Defiance to Salemi | 4,885.08 mi (7,861.78 km) |
| Defiance to Salerno | 4,846.41 mi (7,799.54 km) |
| Defiance to Salo | 4,474.20 mi (7,200.52 km) |
| Defiance to Salsomaggiore Terme | 4,482.33 mi (7,213.61 km) |
| Defiance to Saluzzo | 4,386.96 mi (7,060.13 km) |
| Defiance to Salzano | 4,539.88 mi (7,306.24 km) |
| Defiance to Samarate | 4,403.15 mi (7,086.19 km) |
| Defiance to San Benedetto del Tronto | 4,715.38 mi (7,588.67 km) |
| Defiance to San Biagio di Callalta | 4,544.28 mi (7,313.31 km) |
| Defiance to San Bonifacio | 4,511.98 mi (7,261.33 km) |
| Defiance to San Casciano in Val di Pesa | 4,576.95 mi (7,365.88 km) |
| Defiance to San Cataldo | 4,950.23 mi (7,966.62 km) |
| Defiance to San Cesareo | 4,717.86 mi (7,592.67 km) |
