| Deerfield Beach to Southern Pines (North Carolina) | 615.58 mi (990.67 km) |
| Deerfield Beach to Southfield (Michigan) | 1,131.30 mi (1,820.66 km) |
| Deerfield Beach to Southgate (Michigan) | 1,112.32 mi (1,790.11 km) |
| Deerfield Beach to Southlake (Texas) | 1,118.96 mi (1,800.80 km) |
| Deerfield Beach to Spanaway (Washington) | 2,701.78 mi (4,348.09 km) |
| Deerfield Beach to Spanish Fork (Utah) | 2,041.10 mi (3,284.83 km) |
| Deerfield Beach to Spanish Lake (Missouri) | 1,041.78 mi (1,676.59 km) |
| Deerfield Beach to Spanish Springs (Nevada) | 2,446.53 mi (3,937.31 km) |
| Deerfield Beach to Sparks (Nevada) | 2,448.00 mi (3,939.67 km) |
| Deerfield Beach to Spartanburg (South Carolina) | 606.36 mi (975.85 km) |
| Deerfield Beach to Spearfish (South Dakota) | 1,819.97 mi (2,928.97 km) |
| Deerfield Beach to Speedway (Indiana) | 996.43 mi (1,603.60 km) |
| Deerfield Beach to Spencer (Iowa) | 1,438.03 mi (2,314.28 km) |
| Deerfield Beach to Spokane (Washington) | 2,495.61 mi (4,016.30 km) |
| Deerfield Beach to Spokane Valley (Washington) | 2,486.99 mi (4,002.42 km) |
