| Dana Point to Enumclaw (Washington) | 974.72 mi (1,568.66 km) |
| Dana Point to Ephrata (Pennsylvania) | 2,320.60 mi (3,734.65 km) |
| Dana Point to Erie (Colorado) | 833.44 mi (1,341.29 km) |
| Dana Point to Erie (Pennsylvania) | 2,120.27 mi (3,412.24 km) |
| Dana Point to Erlanger (Kentucky) | 1,873.52 mi (3,015.15 km) |
| Dana Point to Escanaba (Michigan) | 1,821.08 mi (2,930.74 km) |
| Dana Point to Escondido (California) | 42.98 mi (69.17 km) |
| Dana Point to Española (New Mexico) | 682.51 mi (1,098.39 km) |
| Dana Point to Essex (Maryland) | 2,309.24 mi (3,716.37 km) |
| Dana Point to Essex Junction (Vermont) | 2,478.45 mi (3,988.68 km) |
| Dana Point to Estelle (Louisiana) | 1,637.21 mi (2,634.83 km) |
| Dana Point to Estero (Florida) | 2,192.28 mi (3,528.13 km) |
| Dana Point to Euclid (Ohio) | 2,043.57 mi (3,288.81 km) |
| Dana Point to Eufaula (Alabama) | 1,887.87 mi (3,038.24 km) |
| Dana Point to Eugene (Oregon) | 786.91 mi (1,266.41 km) |
