| Costa Mesa to Storm Lake (Iowa) | 1,375.31 mi (2,213.35 km) |
| Costa Mesa to Storrs (Connecticut) | 2,526.79 mi (4,066.47 km) |
| Costa Mesa to Stoughton (Wisconsin) | 1,671.77 mi (2,690.45 km) |
| Costa Mesa to Stow (Ohio) | 2,051.63 mi (3,301.79 km) |
| Costa Mesa to Streamwood (Illinois) | 1,711.66 mi (2,754.66 km) |
| Costa Mesa to Streator (Illinois) | 1,668.48 mi (2,685.17 km) |
| Costa Mesa to Streetsboro (Ohio) | 2,056.45 mi (3,309.54 km) |
| Costa Mesa to Strongsville (Ohio) | 2,031.53 mi (3,269.43 km) |
| Costa Mesa to Stuart (Florida) | 2,275.33 mi (3,661.79 km) |
| Costa Mesa to Stuarts Draft (Virginia) | 2,182.24 mi (3,511.98 km) |
| Costa Mesa to Sturgis (Michigan) | 1,849.78 mi (2,976.93 km) |
| Costa Mesa to Suamico (Wisconsin) | 1,756.36 mi (2,826.60 km) |
| Costa Mesa to Sudley (Virginia) | 2,261.76 mi (3,639.95 km) |
| Costa Mesa to Suffern (New York) | 2,430.92 mi (3,912.19 km) |
| Costa Mesa to Suffolk (Virginia) | 2,322.30 mi (3,737.38 km) |
