| Costa Mesa to Smyrna (Delaware) | 2,360.48 mi (3,798.83 km) |
| Costa Mesa to Smyrna (Georgia) | 1,909.74 mi (3,073.43 km) |
| Costa Mesa to Smyrna (Tennessee) | 1,779.82 mi (2,864.35 km) |
| Costa Mesa to Snellville (Georgia) | 1,938.88 mi (3,120.32 km) |
| Costa Mesa to Snoqualmie (Washington) | 979.38 mi (1,576.16 km) |
| Costa Mesa to Snyder (Texas) | 984.17 mi (1,583.86 km) |
| Costa Mesa to Socastee (South Carolina) | 2,223.33 mi (3,578.10 km) |
| Costa Mesa to Socorro (Texas) | 691.84 mi (1,113.42 km) |
| Costa Mesa to Soddy-Daisy (Tennessee) | 1,859.90 mi (2,993.22 km) |
| Costa Mesa to Solana Beach (California) | 59.94 mi (96.47 km) |
| Costa Mesa to Soledad (California) | 272.76 mi (438.96 km) |
| Costa Mesa to Solon (Ohio) | 2,052.08 mi (3,302.50 km) |
| Costa Mesa to Somers Point (New Jersey) | 2,413.77 mi (3,884.59 km) |
| Costa Mesa to Somerset (Kentucky) | 1,881.30 mi (3,027.67 km) |
| Costa Mesa to Somerset (New Jersey) | 2,414.04 mi (3,885.02 km) |
