| Costa Mesa to Security-Widefield (Colorado) | 814.27 mi (1,310.44 km) |
| Costa Mesa to Sedalia (Missouri) | 1,414.86 mi (2,276.99 km) |
| Costa Mesa to Sedro-Woolley (Washington) | 1,049.57 mi (1,689.12 km) |
| Costa Mesa to Seguin (Texas) | 1,204.67 mi (1,938.73 km) |
| Costa Mesa to Selden (New York) | 2,488.79 mi (4,005.32 km) |
| Costa Mesa to Selma (Alabama) | 1,783.99 mi (2,871.05 km) |
| Costa Mesa to Selma (California) | 222.52 mi (358.11 km) |
| Costa Mesa to Selma (Texas) | 1,185.06 mi (1,907.17 km) |
| Costa Mesa to Seminole (Florida) | 2,113.85 mi (3,401.91 km) |
| Costa Mesa to Seven Hills (Ohio) | 2,039.96 mi (3,283.00 km) |
| Costa Mesa to Seven Oaks (South Carolina) | 2,098.37 mi (3,377.00 km) |
| Costa Mesa to Severn (Maryland) | 2,303.13 mi (3,706.54 km) |
| Costa Mesa to Severna Park (Maryland) | 2,310.14 mi (3,717.81 km) |
| Costa Mesa to Sevierville (Tennessee) | 1,945.22 mi (3,130.53 km) |
| Costa Mesa to Seymour (Indiana) | 1,810.18 mi (2,913.20 km) |
