| Costa Mesa to San Diego (California) | 73.64 mi (118.50 km) |
| Costa Mesa to San Diego Country Estates (California) | 79.29 mi (127.61 km) |
| Costa Mesa to San Dimas (California) | 31.09 mi (50.03 km) |
| Costa Mesa to San Fernando (California) | 52.38 mi (84.29 km) |
| Costa Mesa to San Francisco (California) | 379.96 mi (611.48 km) |
| Costa Mesa to San Gabriel (California) | 31.44 mi (50.60 km) |
| Costa Mesa to San Germán (Puerto Rico) | 3,304.44 mi (5,317.98 km) |
| Costa Mesa to San Jacinto (California) | 53.73 mi (86.47 km) |
| Costa Mesa to San Jose (California) | 334.68 mi (538.62 km) |
| Costa Mesa to San Juan (Puerto Rico) | 3,350.19 mi (5,391.60 km) |
| Costa Mesa to San Juan (Texas) | 1,288.26 mi (2,073.25 km) |
| Costa Mesa to San Juan Capistrano (California) | 18.81 mi (30.27 km) |
| Costa Mesa to San Leandro (California) | 366.97 mi (590.57 km) |
| Costa Mesa to San Lorenzo (California) | 364.24 mi (586.18 km) |
| Costa Mesa to San Luis (Arizona) | 202.52 mi (325.92 km) |
