| Costa Mesa to Shoreham-by-Sea | 5,477.96 mi (8,815.92 km) |
| Costa Mesa to Shotley Bridge | 5,246.54 mi (8,443.49 km) |
| Costa Mesa to Shrewsbury | 5,313.29 mi (8,550.92 km) |
| Costa Mesa to Sidcup | 5,463.05 mi (8,791.94 km) |
| Costa Mesa to Sidmouth | 5,386.06 mi (8,668.03 km) |
| Costa Mesa to Sileby | 5,365.17 mi (8,634.41 km) |
| Costa Mesa to Sittingbourne | 5,487.53 mi (8,831.32 km) |
| Costa Mesa to Skegness | 5,392.02 mi (8,677.62 km) |
| Costa Mesa to Skelmersdale | 5,275.78 mi (8,490.55 km) |
| Costa Mesa to Skipton | 5,281.67 mi (8,500.03 km) |
| Costa Mesa to Sleaford | 5,375.14 mi (8,650.45 km) |
| Costa Mesa to Slough | 5,436.98 mi (8,749.98 km) |
| Costa Mesa to Small Heath | 5,353.18 mi (8,615.11 km) |
| Costa Mesa to Smethwick | 5,348.15 mi (8,607.01 km) |
| Costa Mesa to Snaresbrook | 5,452.87 mi (8,775.54 km) |
