| Coos Bay to Southern Pines (North Carolina) | 2,432.46 mi (3,914.67 km) |
| Coos Bay to Southfield (Michigan) | 2,052.72 mi (3,303.53 km) |
| Coos Bay to Southgate (Michigan) | 2,060.63 mi (3,316.27 km) |
| Coos Bay to Southlake (Texas) | 1,628.05 mi (2,620.09 km) |
| Coos Bay to Spanaway (Washington) | 271.60 mi (437.10 km) |
| Coos Bay to Spanish Fork (Utah) | 686.50 mi (1,104.82 km) |
| Coos Bay to Spanish Lake (Missouri) | 1,787.36 mi (2,876.48 km) |
| Coos Bay to Spanish Springs (Nevada) | 349.00 mi (561.65 km) |
| Coos Bay to Sparks (Nevada) | 351.74 mi (566.07 km) |
| Coos Bay to Spartanburg (South Carolina) | 2,313.78 mi (3,723.67 km) |
| Coos Bay to Spearfish (South Dakota) | 1,016.14 mi (1,635.32 km) |
| Coos Bay to Speedway (Indiana) | 1,961.44 mi (3,156.63 km) |
| Coos Bay to Spencer (Iowa) | 1,455.76 mi (2,342.81 km) |
| Coos Bay to Spokane (Washington) | 442.57 mi (712.25 km) |
| Coos Bay to Spokane Valley (Washington) | 449.54 mi (723.47 km) |
