| Columbus to University Place (Washington) | 2,018.15 mi (3,247.89 km) |
| Columbus to Upland (California) | 1,941.76 mi (3,124.96 km) |
| Columbus to Upper Arlington (Ohio) | 5.31 mi (8.55 km) |
| Columbus to Upper Grand Lagoon (Florida) | 695.86 mi (1,119.87 km) |
| Columbus to Upper Montclair (New Jersey) | 465.71 mi (749.49 km) |
| Columbus to Urbana (Illinois) | 275.75 mi (443.78 km) |
| Columbus to Urbana (Maryland) | 303.56 mi (488.53 km) |
| Columbus to Urbana (Ohio) | 41.52 mi (66.82 km) |
| Columbus to Urbandale (Iowa) | 575.57 mi (926.28 km) |
| Columbus to Utica (New York) | 454.92 mi (732.13 km) |
| Columbus to Uvalde (Texas) | 1,207.19 mi (1,942.78 km) |
| Columbus to Vacaville (California) | 2,074.39 mi (3,338.41 km) |
| Columbus to Vadnais Heights (Minnesota) | 621.13 mi (999.61 km) |
| Columbus to Vail (Arizona) | 1,635.56 mi (2,632.18 km) |
| Columbus to Valdosta (Georgia) | 631.45 mi (1,016.22 km) |
