| Columbus to Santa Rosa (California) | 2,111.34 mi (3,397.87 km) |
| Columbus to Santaquin (Utah) | 1,518.55 mi (2,443.88 km) |
| Columbus to Santee (California) | 1,940.66 mi (3,123.19 km) |
| Columbus to Sapulpa (Oklahoma) | 764.19 mi (1,229.85 km) |
| Columbus to Saraland (Alabama) | 693.65 mi (1,116.32 km) |
| Columbus to Sarasota (Florida) | 874.22 mi (1,406.93 km) |
| Columbus to Sarasota Springs (Florida) | 876.42 mi (1,410.46 km) |
| Columbus to Saratoga (California) | 2,098.84 mi (3,377.76 km) |
| Columbus to Saratoga Springs (New York) | 521.33 mi (839.00 km) |
| Columbus to Saratoga Springs (Utah) | 1,520.85 mi (2,447.57 km) |
| Columbus to Sartell (Minnesota) | 688.79 mi (1,108.50 km) |
| Columbus to Satellite Beach (Florida) | 827.08 mi (1,331.06 km) |
| Columbus to Sauk Rapids (Minnesota) | 685.28 mi (1,102.85 km) |
| Columbus to Sault Ste. Marie (Michigan) | 454.17 mi (730.92 km) |
| Columbus to Savage (Minnesota) | 623.10 mi (1,002.79 km) |
