| Columbus to Oswego (Illinois) | 303.28 mi (488.08 km) |
| Columbus to Oswego (New York) | 411.12 mi (661.63 km) |
| Columbus to Otsego (Minnesota) | 651.35 mi (1,048.24 km) |
| Columbus to Ottawa (Illinois) | 320.29 mi (515.45 km) |
| Columbus to Ottawa (Kansas) | 662.95 mi (1,066.91 km) |
| Columbus to Ottumwa (Iowa) | 500.45 mi (805.39 km) |
| Columbus to Overland (Missouri) | 404.34 mi (650.72 km) |
| Columbus to Overland Park (Kansas) | 628.56 mi (1,011.57 km) |
| Columbus to Overlea (Maryland) | 346.56 mi (557.73 km) |
| Columbus to Oviedo (Florida) | 789.35 mi (1,270.33 km) |
| Columbus to Owasso (Oklahoma) | 742.54 mi (1,195.00 km) |
| Columbus to Owatonna (Minnesota) | 596.77 mi (960.40 km) |
| Columbus to Owensboro (Kentucky) | 270.34 mi (435.07 km) |
| Columbus to Owings Mills (Maryland) | 331.61 mi (533.67 km) |
| Columbus to Owosso (Michigan) | 216.85 mi (348.99 km) |
